Welcome to the Laboratory of Asymmetric Catalysis and Synthesis headed by Professor Nicolai Cramer. We are a young and dynamic research team working on challenges in the areas of asymmetric metal-catalyzed reactions and the synthesis of bioactive natural products.
30.08.2018: Daria’s work on the enantioselective Pd-catalyzed synthesis of 1H-isoindoles got published in ACIE, congrats!!!
25.07.2018: The paper from Yun-Suk, Lukasz and Julia on iridium-catalyzed atropselective biaryl synthesis appeared in ACIE, congrats!!!
20.07.2018: Mischa successfully defended his Master Thesis on the synthesis of phalloidins, congrats!
02.07.2018: Chris, Elena and Jenny’s work on atropoenantioselective cyclization appeared in ACIE, big congrats!
01.05.2018: Dr. Ana Pascual Escudero joins the group for a postdoc. Welcome Ana!
01.04.2018: Dr. Gints Smits comes to the LCSA for a short visits. Weclome back!
16.3.2018: Johannes paper on enantioselective Ni-catalyzed pyridone functionalization appeared in JACS, congrats!!
12.03.2018: Shuo-Guo and Sung Hwan’s paper on a 2-step chiral Cp-ligand family appeared in Angewandte Chemie, congrats!
01.03.2018: Dr. Maria Frias joins the group for a postdoc. Welcome!
20.02.2018: Jack and Solène’s work on asymmetric diazaphospholene catalysis appeared in Angewandte Chemie, congrats!
19.02.2018: Mischa Schüttel started his Master thesis on natural product synthesis, welcome back to EPFL!
01.02.2018: Dr. Marcus Brauns joins the group for a postdoc, welcome to Lausanne.
01.02.2018: Vitalii Smal from Saclay joins the group for his Master work, welcome!
15.01.2018: Yang’s kinetic resolution to generate P-chiral compounds appeared in Chem. Science, congrats!
02.01.2018: Dr. Lukasz Wozniak joins the group for his postdoc. Welcome!
01.11.2017: After defending her Master in Italy, Elena Braconi is back in the group for her PhD thesis, welcome back!
01.10.2017: Kristers Ozols joins the group for his PhD thesis, welcome Kristers!
26.09.2017: Daria’s work on enantioselective ketene aminal phosphate C-H functionalization is published in ACS Catalysis, congrats!
01.09.2017: Jin Fay Tan starts his PhD in the group, welcome to Lausanne!
J. Diesel, A. Finogenova, N. Cramer, J. Am. Chem. Soc. 2018, DOI:10.1021/jacs.8b01181: “Nickel-Catalyzed Enantioselective Pyridone C-H Functionalizations Enabled by a Bulky N-Heterocyclic Carbene Ligand”
S.-G. Wang, S. H. Park, N. Cramer, Angew. Chem. Int. Ed. 2018, DOI:10.1002/anie.201802244: “A Readily Accessible Class of Chiral Cp Ligands and their Application in Ru(II)-Catalyzed Enantioselective Syntheses of Dihydrobenzoindoles”
S. Miaskiewicz, J. H. Reed, P. A. Donets, C. C. Oliveira, N. Cramer, Angew. Chem. Int. Ed. 2018,
Y. Sun, N. Cramer, Chem. Sci. 2018, DOI:10.1039/c7sc05411d: “Tailored trisubstituted chiral CpxRhIII catalysts for kinetic resolutions of phosphinic amides”
D. Grosheva, N. Cramer, ACS Catalysis 2017, 7, 7417-7420: “Ketene Aminal Phosphates: Competent Substrates for Enantioselective Pd(0)-Catalyzed C-H Functionalizations”
Y.-S. Jang, M. Dieckmann, N. Cramer, Angew. Chem. Int. Ed. 2017, 56, 15088-15092: “Cooperative Effects between Chiral CpxIrIII Catalysts and Chiral Carboxylic Acids in Enantioselective C-H Amidations of Phosphine Oxides”